Don’t let nostalgia for CS6 or the lure of “portable free” put your digital security at risk. The safest download is the one you never have to question.

Technically, yes—but with major caveats. Several cracking groups (like PortableAppZ, JooSoft, and Xanza) have created modified versions of CS6 that run without installation. However:

What “portable” and “Softonic” mean

A is a program that does not write settings or files to the Windows Registry or the user's AppData folder. Instead, it stores all configuration files inside its own folder.

Let's look at the part of your search. Softonic is a legitimate Spanish software download site founded in 1997. It aggregates both freeware, trialware, and open-source software.