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The "nurturing nurse" trope is one of the most enduring in the genre. Digital Playground took this classic trope and gave it a modern, high-budget polish.

: Plays the daughter of Dr. Ben English. Her "sex-crazed" behavior adds stress to her father's health. Kayden Kross & Jesse Jane : Compete for the attention of Dr. Manuel Ferrara Riley Steele : Portrays an aspiring model nurse interacting with Erik Everhard Alexis Texas : Featured as a patient seeking treatment from Dr. James Deen Selena Rose

Bibi Jones was arguably the biggest contract star of the early 2010s. Her appeal was her "girl-next-door" aesthetic combined with an unapologetic sexual energy. In Nurses 2 , she headlines the cast and carries the weight of the marketing.