Major editions (Ed.1, Ed.2, Ed.3, Ed.4) are released every 4-6 years. Interim updates may appear in the CLSI M100 supplement. Always check the "Current Editions" page on the CLSI website.
CLSI document M45 provides guidance on antimicrobial susceptibility testing (AST) and interpretation for Enterobacterales that produce extended-spectrum β-lactamases (ESBLs) and other β-lactamases that compromise β-lactam therapy. It focuses on practical laboratory methods, breakpoints, reporting recommendations, and interpretive comments to improve clinical relevance and patient care when dealing with ESBL-producing organisms. clsi document m45 pdf
. It offers specialized protocols for 14 organism groups, including Listeria monocytogenes , filling gaps left by more general guidelines Clinical & Laboratory Standards Institute | CLSI . For more details, visit Major editions (Ed
The latest or updates for the 3rd Edition. It offers specialized protocols for 14 organism groups,
The CLSI M45 standard provides guidelines for the performance of antimicrobial disk diffusion susceptibility tests for bacteria isolated from animals. The standard aims to ensure that laboratories perform accurate and reliable susceptibility tests to guide veterinarians in selecting effective antimicrobial therapies.