Once The Homebrew Channel is installed, download a USB loader application:

The Wii’s original I/O system cannot read ISOs from USB. (custom IOS) patches the system to allow USB loading. We’ll use the popular d2x cIOS .

Did you know the Wii can also play GameCube ISOs? Install (a loader that runs GameCube games). Place your GameCube ISOs in a /games/ folder with the naming convention: Game Name [GameID]/game.iso . Nintendont supports virtual memory cards and even lets you use a Wii Remote or a USB controller instead of a GameCube controller.