Twixtor is notoriously sensitive to the host environment (After Effects, Premiere Pro, DaVinci Resolve).
If you have a paid license but Twixtor still asks for an "activation file," try these steps: twixtor pro v7 activation file
Ensure you have the latest drivers, as version 7 significantly improved GPU utilization to reduce the "stuttery" playback often found in older versions. Twixtor is notoriously sensitive to the host environment